Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19735703 | 1.00 | MEN1 (0.50) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19735672 | 1.00 | MEN1 (0.50) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL29506706 | 0.91 | MEN1 (0.59) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL283196 | 0.91 | MEN1 (0.59) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL17816646 | 0.89 | MEN1 (0.57) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL105865 | 0.87 | MEN1 (0.63) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL30288909 | 0.87 | MEN1 (0.63) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL28135141 | 0.87 | MEN1 (0.63) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19735693 | 0.87 | LMNA (0.43) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19735694 | 0.87 | LMNA (0.43) | MEN1KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369719-B1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-26 | — | — | EP | disclosed |