SCHEMBL21763554

SCHEMBL21763554

Ic1cccc2c(I)c3ccccc3cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.44
HSD17B10 Q99714 7/20 0.44
HIF1A Q16665 2/20 0.44
CYP1B1 Q16678 1/20 0.44
KDM4E B2RXH2 2/20 0.37
GAA P10253 1/20 0.37
CYP1A2 P05177 7/20 0.36
HPGD P15428 5/20 0.36
TSHR P16473 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
TRPM4 Q8TD43 1/20 0.35
CYP2A6 P11509 4/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2222268 0.84 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL16723362 0.81 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL1133128 0.81 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL4614015 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL31108395 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL20726219 0.79 ALDH1A1 (0.56) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL29137699 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL21360527 0.79 HSD17B10 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
Benzene SCHEMBL4082384 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL26467980 0.79 CYP1A2 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11034840-B2 Water-soluble polymeric dyes BECTON, DICKINSON AND COMPANY (US) 2021-06-15 US disclosed
US-20200062966-A1 Water-Soluble Polymeric Dyes BECTON, DICKINSON AND COMPANY 2020-02-27 US disclosed