Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15755388 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL30229923 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL15755737 | 0.86 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL30229952 | 0.86 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL24071016 | 0.78 | CYP3A4 (0.54) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL30230025 | 0.78 | CYP3A4 (0.54) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL15755196 | 0.78 | TDP1 (0.43) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL30230234 | 0.78 | TDP1 (0.43) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL15761584 | 0.76 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 | |
| SCHEMBL15756000 | 0.76 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C19MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062700-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX LLC (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062700-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | EIF2AK2, TP53, KRAS | CYP1A2 3855/4885CYP3A4 4387/4885CYP2C19 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.