Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230025 | 1.00 | CYP3A4 (0.54) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL15756000 | 0.90 | CYP1A2 (0.61) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL15761586 | 0.86 | CYP1A2 (0.64) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL25749472 | 0.84 | MAPT (0.48) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL24071014 | 0.83 | MAPK1 (0.54) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL24071015 | 0.81 | MAPK1 (0.52) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL15761594 | 0.81 | MAPT (0.74) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL21763772 | 0.78 | CYP1A2 (0.50) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL30229904 | 0.78 | CYP1A2 (0.58) | CYP3A4CYP1A2CYP2C19MAPTMAPK1 | |
| SCHEMBL1410405 | 0.77 | ACP1 (0.52) | PLA2G1BATG4BACP1PPARGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201144-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | NOVOMEDIX, LLC (US) | 2023-06-29 | — | — | US | disclosed |
| WO-2021243319-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | NOVOMEDIX, LLC (US) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201144-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | FAH, COASY, ARSA | CYP3A4 574/4885CYP1A2 301/4885CYP2C19 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.