Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177973 | 0.84 | MAPK14 (0.46) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2175647 | 0.82 | MAPK14 (0.51) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2178922 | 0.82 | MAPK14 (0.66) | NPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2175391 | 0.78 | MAPK14 (0.46) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2180062 | 0.78 | KDM4E (0.40) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2175574 | 0.78 | MAPK14 (0.41) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2178029 | 0.77 | HSP90AA1 (0.43) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2180037 | 0.77 | KDM4E (0.39) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2177726 | 0.77 | MCHR1 (0.41) | KDM4ENPC1ALDH1A1HPGDMAPK14 | |
| SCHEMBL2174324 | 0.77 | MAPK14 (0.41) | KDM4ENPC1ALDH1A1HPGDMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135465-A1 | Fab I Inhibitor and Process for Preparing Same | CRYSTALGENOMICS, INC. (KR) | 2007-06-14 | — | — | US | claimed |
| US-7973060-B2 | Fab I inhibitor and process for preparing same | CRYSTALGENOMICS, INC. (KR) | 2011-07-05 | — | — | US | disclosed |
| US-20070135465-A1 | Fab I Inhibitor and Process for Preparing Same | CRYSTALGENOMICS, INC. (KR) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135465-A1 | Fab I Inhibitor and Process for Preparing Same | TFPI, TFPI2, FCGRT | KDM4E 3785/4885NPC1 402/4885ALDH1A1 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.