SCHEMBL2178922

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2175647	0.89	MAPK14 (0.51)	MAPK14MAOBMCHR1MAOANPC1
	SCHEMBL2177276	0.89	MAPK14 (0.52)	MAPK14MAOBMCHR1MAOA
	SCHEMBL2175391	0.85	MAPK14 (0.46)	MAPK14MCHR1NPC1ALDH1A1HPGD
	SCHEMBL2177973	0.85	MAPK14 (0.46)	MAPK14MCHR1NPC1ALDH1A1HPGD
	SCHEMBL2176064	0.83	MAPK14 (0.78)	MAPK14MCHR1S1PR1PRKXACVR1
	SCHEMBL2177300	0.82	MAPK14 (0.72)	MAPK14MCHR1
	SCHEMBL2175674	0.82	MAPK14 (0.72)	MAPK14MCHR1S1PR1PRKXACVR1
	SCHEMBL2176386	0.82	KDM4E (0.45)	MAPK14NPC1ALDH1A1HPGD
	SCHEMBL2174324	0.82	MAPK14 (0.41)	MAPK14MAOBMCHR1NPC1ALDH1A1
	SCHEMBL27736829	0.81	MAOB (0.52)	MAPK14MAOBS1PR1PRKXACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.