Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23504623 | 0.94 | LPL (0.47) | LPLLIPGPRMT5WDR77P4HB | |
| SCHEMBL31062339 | 0.84 | KDM4E (0.51) | LPLLIPGPRMT5WDR77KDM4E | |
| SCHEMBL25908152 | 0.84 | KDM4E (0.51) | LPLLIPGPRMT5WDR77KDM4E | |
| SCHEMBL47074 | 0.83 | LPL (0.53) | LPLLIPGP4HBROCK1CA1 | |
| SCHEMBL16581306 | 0.83 | LPL (0.56) | LPLLIPGPRMT5WDR77P4HB | |
| SCHEMBL17072840 | 0.81 | LPL (0.47) | LPLLIPGPRMT5WDR77P4HB | |
| SCHEMBL19530897 | 0.80 | LPL (0.41) | LPLLIPGPRMT5WDR77P4HB | |
| SCHEMBL34467622 | 0.80 | LPL (0.41) | LPLLIPGPRMT5WDR77P4HB | |
| SCHEMBL20222384 | 0.80 | LPL (0.41) | LPLLIPGPRMT5WDR77P4HB | |
| SCHEMBL25908302 | 0.80 | KDM4E (0.53) | LPLLIPGPRMT5WDR77P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227269-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |