Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 5/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21764939 | 0.82 | USP2 (0.43) | HRH3POLBELANEKDM4EITGB3 | |
| SCHEMBL9963250 | 0.81 | CYP2D6 (0.50) | MEN1KMT2AITGB3ITGA2BMETAP2 | |
| Hydrochloric Acid SCHEMBL21753301 | 0.81 | USP2 (0.42) | HRH3POLBELANEKDM4EITGB3 | |
| SCHEMBL21753321 | 0.78 | ITGB3 (0.48) | ELANEMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL21765127 | 0.75 | OGA (0.49) | LIPEMETAP2 | |
| SCHEMBL21765218 | 0.75 | OGA (0.49) | LIPEMETAP2 | |
| SCHEMBL21765128 | 0.75 | OGA (0.49) | LIPEMETAP2 | |
| SCHEMBL21753327 | 0.74 | HRH3 (0.55) | HRH3ALDH1A1ITGB3ITGA2B | |
| SCHEMBL23384006 | 0.71 | KDM4E (0.61) | HRH3POLBKDM4EALDH1A1MAPT | |
| SCHEMBL5429590 | 0.71 | CYP3A4 (0.41) | POLBMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039029-A1 | SPIRO COMPOUNDS AS GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |