Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PARG | Q86W56 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30543497 | 0.99 | USP2 (0.48) | USP2TSHRCYP2D6SMN1; SMN2HTR2C | |
| SCHEMBL26037607 | 0.89 | HSD11B1 (0.48) | USP2TSHRCYP2D6SMN1; SMN2PARG | |
| SCHEMBL21764932 | 0.86 | USP2 (0.50) | USP2TSHRCYP2D6SMN1; SMN2HTR2C | |
| Hydrochloric Acid SCHEMBL21753290 | 0.85 | USP2 (0.49) | USP2TSHRCYP2D6SMN1; SMN2HTR2C | |
| SCHEMBL13043453 | 0.82 | CMA1 (0.52) | MEN1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3390878 | 0.81 | CMA1 (0.51) | MEN1KMT2AMAPTALDH1A1 | |
| Bromide SCHEMBL17141069 | 0.81 | USP2 (0.47) | USP2TSHRCYP2D6SMN1; SMN2HTR2C | |
| SCHEMBL17140413 | 0.80 | USP2 (0.49) | USP2TSHRCYP2D6SMN1; SMN2HTR2C | |
| Bromide SCHEMBL18940775 | 0.79 | USP2 (0.48) | USP2TSHRCYP2D6SMN1; SMN2HTR2C | |
| SCHEMBL21753296 | 0.78 | CYP3A4 (0.48) | USP2TSHRCYP2D6SMN1; SMN2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039029-A1 | SPIRO COMPOUNDS AS GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |