Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21151348 | 0.84 | POLB (0.51) | POLBELANENPC1RAB9ADGAT1 | |
| Hydrochloric Acid SCHEMBL21753212 | 0.83 | POLB (0.50) | POLBELANENPC1RAB9ADGAT1 | |
| SCHEMBL19534078 | 0.81 | POLB (0.54) | POLBELANENPC1RAB9AEGLN1 | |
| SCHEMBL21151347 | 0.79 | GPR119 (0.48) | POLBELANEDGAT1MCHR1TACR1 | |
| SCHEMBL1773546 | 0.77 | AR (0.68) | PGRAR | |
| SCHEMBL26041437 | 0.73 | NPC1 (0.38) | POLBELANENPC1RAB9ADGAT1 | |
| SCHEMBL7037195 | 0.72 | AR (0.46) | POLBOPRM1HTR2BAR | |
| SCHEMBL23288931 | 0.71 | POLB (0.50) | POLBELANENPC1RAB9ADGAT1 | |
| SCHEMBL21151794 | 0.70 | ELANE (0.56) | POLBELANEPGROPRM1AR | |
| SCHEMBL24974458 | 0.70 | HIF1A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039029-A1 | SPIRO COMPOUNDS AS GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |