Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.63 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.61 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.61 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.60 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145754 | 0.83 | KMT2A (0.62) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8914692 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4268296 | 0.81 | MAPT (0.59) | SMN1; SMN2ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL5545852 | 0.81 | CYP2C19 (0.60) | SMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL2959279 | 0.81 | HIF1A (0.82) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9911424 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9912441 | 0.80 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28172169 | 0.80 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18204569 | 0.80 | STAT3 (0.55) | RAB9AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10632034 | 0.79 | MAPT (0.60) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200061225-A1 | ALDEHYDE SCAVENGER AND METHOD FOR REMOVING ALDEHYDES | TOSOH CORPORATION (JP) | 2020-02-27 | — | — | US | disclosed |