Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 14/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389884 | 0.88 | IRAK4 (0.62) | IRAK4TNF | |
| SCHEMBL21379216 | 0.88 | IRAK4 (0.62) | IRAK4TNF | |
| SCHEMBL31436626 | 0.85 | IRAK4 (0.53) | IRAK4TNF | |
| SCHEMBL26598727 | 0.85 | IRAK4 (0.53) | IRAK4TNF | |
| SCHEMBL31678570 | 0.83 | IRAK4 (0.44) | IRAK4TNF | |
| SCHEMBL16873023 | 0.81 | IRAK4 (0.40) | IRAK4TNF | |
| SCHEMBL21765615 | 0.81 | IRAK4 (0.57) | IRAK4NPC1RAB9A | |
| SCHEMBL15688948 | 0.79 | IRAK4 (0.53) | IRAK4KMT2ATNF | |
| SCHEMBL21765491 | 0.78 | IRAK4 (0.75) | IRAK4TNF | |
| SCHEMBL21949096 | 0.78 | CA1 (0.54) | IRAK4GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475270-B1 | HETEROARYL SUBSTITUTED AMINOPYRIDINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-02-26 | — | — | EP | disclosed |