Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AANAT | Q16613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366699 | 0.89 | MAPK1 (0.47) | HPGDALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL3623817 | 0.82 | HPGD (0.65) | HPGDALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL2251775 | 0.82 | HDAC3 (0.61) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1939816 | 0.81 | MAPK1 (0.50) | HPGDALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL29531243 | 0.81 | MAPK1 (0.50) | HPGDALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL21765656 | 0.79 | HDAC3 (0.50) | HPGDALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL28822093 | 0.79 | HTT (0.47) | HPGDALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL32665522 | 0.79 | TSHR (0.53) | HPGDAANATKDM4E | |
| SCHEMBL29025528 | 0.78 | L3MBTL1 (0.62) | HPGDALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL23134945 | 0.77 | HPGD (0.57) | HPGDALDH1A1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |