Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801270 | 0.82 | — | — | |
| SCHEMBL10106488 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1CA2CYP2C19CHRNB2 | |
| SCHEMBL5367268 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2CYP2C19CHRNB2 | |
| SCHEMBL12734485 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2CYP2C19MMP1 | |
| SCHEMBL27522034 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2CYP2C19CHRNB2 | |
| SCHEMBL16197744 | 0.75 | ALDH1A1 (0.32) | ALDH1A1TDP1CA2 | |
| SCHEMBL27269038 | 0.74 | — | — | |
| SCHEMBL10106489 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TDP1CA2CYP2C19SMN1; SMN2 | |
| SCHEMBL19432396 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TDP1CA2CYP2C19 | |
| SCHEMBL17919862 | 0.74 | TDP1 (0.40) | ALDH1A1TDP1CA2CYP2C19CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261257-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |