Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444915 | 0.91 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL194101 | 0.91 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL194100 | 0.91 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL7324302 | 0.83 | MME (0.44) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL7324309 | 0.83 | MME (0.44) | MMERAB9AACECPA1ACE2 | |
| Aspartic Acid SCHEMBL7173783 | 0.81 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1LTA4H | |
| Alanine SCHEMBL9180204 | 0.80 | CA1 (0.46) | CA2CA1KDM4E | |
| SCHEMBL204822 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2CA2CA1TYRALDH1A1 | |
| D-Alanine SCHEMBL6865373 | 0.77 | ALDH1A1 (0.43) | MMERAB9AACECPA1ACE2 | |
| Alanine SCHEMBL20898432 | 0.77 | ALDH1A1 (0.43) | MMERAB9AACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519506-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082077-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |