Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112131 | 0.90 | TSHR (0.50) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL31590958 | 0.90 | TSHR (0.61) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL3118524 | 0.90 | TSHR (0.56) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL3124622 | 0.90 | TSHR (0.56) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL3108005 | 0.90 | TSHR (0.50) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL4354554 | 0.90 | TSHR (0.61) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL3112778 | 0.90 | TSHR (0.56) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL3127320 | 0.90 | TSHR (0.50) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL3108944 | 0.87 | TSHR (0.52) | TSHRTRPA1ALDH1A1USP2MAPT | |
| SCHEMBL3119730 | 0.87 | TSHR (0.46) | TSHRTRPA1ALDH1A1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548857-B2 | Biodegradable compound, lipid particle, composition comprising lipid particle, and kit | KABUSHIKI KAISHA TOSHIBA (JP) | 2023-01-10 | — | — | US | disclosed |
| US-20200270217-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT | KABUSHIKI KAISHA TOSHIBA (JP) | 2020-08-27 | — | — | US | disclosed |
| WO-2020039631-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLES, COMPOSITION CONTAINING LIPID PARTICLES, AND KIT | 株式会社 東芝 | 2020-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548857-B2 | Biodegradable compound, lipid particle, composition comprising lipid particle, and kit | KIT, NPY1R, CCKAR | TSHR 3869/4885TRPA1 168/4885ALDH1A1 1368/4885 |
| US-20200270217-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT | KIT, NPY1R, CCKAR | TSHR 3869/4885TRPA1 168/4885ALDH1A1 1368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.