Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270637 | 0.89 | PTPN1 (0.56) | PTPN1TP53RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21765873 | 0.89 | PTPN1 (0.88) | PTPN1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL21765706 | 0.83 | MAPK1 (0.68) | PTPN1RAB9ASMN1; SMN2HPGDLMNA | |
| SCHEMBL28688601 | 0.82 | TP53 (0.68) | TP53RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL19002582 | 0.82 | TP53 (0.68) | TP53RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL8434001 | 0.82 | SMN1; SMN2 (0.72) | PTPN1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL6389276 | 0.81 | PTPN1 (0.76) | PTPN1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL8361578 | 0.81 | PTPN1 (0.76) | PTPN1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL19921034 | 0.81 | PTPN1 (0.69) | PTPN1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL10294766 | 0.81 | PTPN1 (0.69) | PTPN1RAB9ASMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |