Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765874 | 0.83 | PTPN1 (0.71) | MAPK1HTTGAAALDH1A1LMNA | |
| SCHEMBL10154842 | 0.81 | HDAC3 (0.58) | POLBGAAALDH1A1LMNAHPGD | |
| SCHEMBL12284941 | 0.81 | SMN1; SMN2 (0.59) | POLBGAAALDH1A1LMNAHPGD | |
| SCHEMBL29315244 | 0.81 | MAPK1 (1.00) | MAPK1HTTGAAALDH1A1LMNA | |
| SCHEMBL19364615 | 0.81 | MAPK1 (0.59) | MAPK1HTTGAAALDH1A1LMNA | |
| SCHEMBL4960066 | 0.79 | HPGD (0.62) | MAPK1POLBGAAALDH1A1LMNA | |
| SCHEMBL22270637 | 0.79 | PTPN1 (0.56) | GAAALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL27713876 | 0.79 | POLB (0.59) | POLBGAAALDH1A1LMNAHPGD | |
| SCHEMBL24485241 | 0.78 | POLB (0.57) | POLBHTTGAAALDH1A1LMNA | |
| SCHEMBL20964580 | 0.78 | HPGD (0.73) | POLBGAAALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |