Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301050 | 0.87 | PTGS1 (0.46) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL1081993 | 0.80 | PTGS1 (0.38) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL17301087 | 0.76 | ALDH1A1 (0.32) | ALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL2494888 | 0.76 | PTGS1 (0.40) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL23339728 | 0.73 | KMT2A (0.35) | PTGS1PTGS2ALDH1A1TP53HPGD | |
| SCHEMBL15252995 | 0.73 | ALDH1A1 (0.40) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL29078555 | 0.72 | KMT2A (0.32) | ALDH1A1HPGDCYP1A2CYP2C19PKM | |
| SCHEMBL20763155 | 0.72 | MME (0.34) | PTGS1PTGS2 | |
| SCHEMBL17453310 | 0.71 | PTGS1 (0.40) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL23339254 | 0.70 | MME (0.33) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949343-B1 | TRIDENTATE CONNEXON AND USE THEREOF | NEWBIO THERAPEUTICS INC (CN) | 2020-02-26 | — | — | EP | disclosed |