Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.31 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
| ▸ | GPR6 | P46095 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766431 | 0.89 | ENPP1 (0.33) | ENPP1STING1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL21766435 | 0.87 | STING1 (0.41) | STING1 | |
| SCHEMBL21766530 | 0.85 | STING1 (0.34) | ENPP1STING1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL21766514 | 0.85 | ENPP1 (0.46) | ENPP1STING1 | |
| SCHEMBL21766535 | 0.78 | STING1 (0.33) | ENPP1STING1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL21766453 | 0.78 | STING1 (0.41) | STING1 | |
| SCHEMBL21766439 | 0.78 | STING1 (0.41) | ENPP1STING1 | |
| SCHEMBL21766501 | 0.77 | ENPP1 (0.32) | ENPP1STING1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL21753416 | 0.76 | STING1 (0.42) | STING1 | |
| SCHEMBL21766301 | 0.74 | ENPP1 (0.48) | ENPP1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842437-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038387-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | 杭州阿诺生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |