Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 7/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.31 |
| ▸ | ITK | Q08881 | 3/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.31 |
| ▸ | PRKCG | P05129 | 2/20 | 0.31 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.31 |
| ▸ | MARK3 | P27448 | 2/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.31 |
| ▸ | CLK2 | P49760 | 2/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.31 |
| ▸ | NEK4 | P51957 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766431 | 0.87 | ENPP1 (0.33) | STING1ENPP1GPR6SLC2A1SLC2A3 | |
| SCHEMBL21753580 | 0.87 | STING1 (0.41) | STING1 | |
| SCHEMBL21766434 | 0.85 | ENPP1 (0.33) | STING1ENPP1GPR6SLC2A1SLC2A3 | |
| SCHEMBL21766535 | 0.79 | STING1 (0.33) | STING1ENPP1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL21766301 | 0.78 | ENPP1 (0.48) | STING1ENPP1 | |
| SCHEMBL21766501 | 0.78 | ENPP1 (0.32) | STING1ENPP1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL23585744 | 0.74 | ABL1 (0.33) | ABL1 | |
| SCHEMBL21753416 | 0.73 | STING1 (0.42) | STING1 | |
| SCHEMBL21766335 | 0.73 | ENPP1 (0.48) | STING1ENPP1 | |
| SCHEMBL21766463 | 0.72 | STING1 (0.39) | STING1ENPP1SLC2A1SLC2A3SLC2A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842437-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038387-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | 杭州阿诺生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |