Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12799428 | 0.83 | MEN1 (0.78) | MEN1KMT2ARECQLCYP1A2CYP2C9 | |
| SCHEMBL19116356 | 0.79 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL145975 | 0.79 | KDM4D (0.39) | KMT2ARECQLTSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL1912202 | 0.79 | MAPK1 (0.48) | TSHRKDM4DALDH1A1MTNR1AMTNR1B | |
| SCHEMBL23011666 | 0.77 | KDM4D (0.35) | MEN1KMT2ARECQLTSHRKDM4D | |
| SCHEMBL5841987 | 0.77 | KDM4D (0.35) | MEN1KMT2ARECQLTSHRKDM4D | |
| SCHEMBL5841992 | 0.77 | KDM4D (0.35) | MEN1KMT2ARECQLTSHRKDM4D | |
| SCHEMBL18362143 | 0.77 | MEN1 (0.56) | MEN1KMT2ARECQLMTNR1AMTNR1B | |
| SCHEMBL3043384 | 0.77 | POLB (0.44) | RECQLKDM4DALDH1A1 | |
| SCHEMBL22917237 | 0.77 | GRIA1 (0.52) | MEN1KMT2ARECQLCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402785-B1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |