Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18246269 | 0.80 | NOS1 (0.38) | NOS1ACHE | |
| SCHEMBL18246168 | 0.80 | NOS1 (0.38) | NOS1ACHE | |
| SCHEMBL28456407 | 0.80 | NOS1 (0.38) | NOS1ACHE | |
| SCHEMBL18245797 | 0.80 | NOS1 (0.38) | NOS1ACHE | |
| SCHEMBL18247281 | 0.80 | NOS1 (0.38) | NOS1ACHE | |
| SCHEMBL15703055 | 0.75 | NOS1 (0.36) | NOS1ACHE | |
| SCHEMBL179278 | 0.75 | — | — | |
| SCHEMBL24023949 | 0.67 | — | — | |
| SCHEMBL22083524 | 0.67 | — | — | |
| SCHEMBL21850519 | 0.67 | MAP4K1 (0.34) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3300500-B1 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-02-26 | — | — | EP | disclosed |