Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL21768091

NC/C(=C\F)COc1ccc(C(=O)Nc2ccc(F)cc2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.60
AOC2 O75106 4/20 0.60
MAOA P21397 3/20 0.60
DAO P14920 2/20 0.60
AOC3 Q16853 5/20 0.59
KMT2A Q03164 3/20 0.50
LMNA P02545 2/20 0.50
MEN1 O00255 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
NPC1 O15118 2/20 0.46
MITF O75030 1/20 0.46
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
STAT5A P42229 1/20 0.44
STAT5B P51692 1/20 0.44
PTPN1 P18031 1/20 0.44
RAB9A P51151 1/20 0.44
CXCR1 P25024 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21768093 1.00 MAOB (0.60) MAOBAOC2MAOADAOAOC3
Trifluoroacetic Acid SCHEMBL21768094 0.91 AOC3 (0.61) MAOBAOC2MAOADAOAOC3
Trifluoroacetic Acid SCHEMBL21768097 0.91 AOC3 (0.61) MAOBAOC2MAOADAOAOC3
Trifluoroacetic Acid SCHEMBL21768092 0.91 AOC3 (0.61) MAOBAOC2MAOADAOAOC3
SCHEMBL21780049 0.85 AOC3 (0.65) MAOBAOC2MAOADAOAOC3
SCHEMBL21780043 0.85 AOC3 (0.65) MAOBAOC2MAOADAOAOC3
Trifluoroacetic Acid SCHEMBL21768176 0.84 MRGPRX4 (0.47) MAOBAOC2MAOADAOAOC3
Trifluoroacetic Acid SCHEMBL21768028 0.84 MRGPRX4 (0.47) MAOBAOC2MAOADAOAOC3
Trifluoroacetic Acid SCHEMBL21768029 0.84 MRGPRX4 (0.47) MAOBAOC2MAOADAOAOC3
Trifluoroacetic Acid SCHEMBL28901249 0.83 RAB9A (0.58) MAOBAOC3KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200087248-A1 Fluoroallylamine Derivative And Use Thereof SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2020-03-19 US disclosed
EP-3617186-A1 FLUOROALLYLAMINE DERIVATIVE AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087248-A1 Fluoroallylamine Derivative And Use Thereof VAPB, VAPA, SLC28A1 MAOB 60/4885AOC2 16/4885MAOA 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.