Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.54 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305131 | 0.93 | CRBN (0.54) | CRBNBRD4DDB1GSPT1IKZF3 | |
| SCHEMBL21751085 | 0.86 | CRBN (0.46) | CRBNBRD4DDB1GSPT1 | |
| SCHEMBL21751120 | 0.85 | CRBN (0.63) | CRBNBRD4DDB1GSPT1IKZF3 | |
| SCHEMBL25767998 | 0.84 | CRBN (0.61) | CRBNDDB1GSPT1IKZF3 | |
| SCHEMBL31305255 | 0.84 | CRBN (0.45) | CRBNDDB1GSPT1 | |
| SCHEMBL21769113 | 0.83 | CRBN (0.44) | CRBNDDB1GSPT1 | |
| SCHEMBL28353726 | 0.83 | CRBN (0.44) | CRBNDDB1GSPT1 | |
| SCHEMBL30600421 | 0.83 | CRBN (0.44) | CRBNDDB1GSPT1 | |
| SCHEMBL28357814 | 0.79 | CRBN (0.61) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL23449280 | 0.79 | CRBN (0.58) | CRBNDDB1GSPT1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623366-B9 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | KOREA RES INST CHEMICAL TECH (KR) | 2022-06-15 | — | — | EP | disclosed |
| EP-3623366-B1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | KOREA RES INST CHEMICAL TECH (KR) | 2022-01-19 | — | — | EP | disclosed |
| US-11192878-B2 | Piperidine-2,6-dione derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-12-07 | — | — | US | disclosed |
| US-20200062730-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062730-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | CRBN, PDCD11, CD47 | CRBN 1/4885BRD4 1236/4885DDB1 153/4885 |
| US-11192878-B2 | Piperidine-2,6-dione derivative and use thereof | CRBN, PDCD11, CD47 | CRBN 1/4885BRD4 1642/4885DDB1 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.