SCHEMBL30600421

SCHEMBL30600421

CO/C=C/c1ccc(CNC(=O)OC(C)(C)C)cc1C(=O)NC1CCC(=O)NC1=O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.44
DDB1 Q16531 6/20 0.44
GSPT1 P15170 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28353726 1.00 CRBN (0.44) CRBNDDB1GSPT1
SCHEMBL21769113 1.00 CRBN (0.44) CRBNDDB1GSPT1
SCHEMBL21751069 0.89 CRBN (0.50) CRBNDDB1GSPT1
SCHEMBL21751072 0.89 CRBN (0.50) CRBNDDB1GSPT1
SCHEMBL31305131 0.84 CRBN (0.54) CRBNDDB1GSPT1
SCHEMBL28353724 0.83 CRBN (0.44) CRBNDDB1
SCHEMBL21769092 0.83 CRBN (0.54) CRBNDDB1GSPT1
SCHEMBL28353655 0.82 CRBN (0.50) CRBNDDB1
SCHEMBL28353660 0.82 CRBN (0.50) CRBNDDB1
SCHEMBL31305255 0.81 CRBN (0.45) CRBNDDB1GSPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110621664-B Novel piperidine-2, 6-dione derivatives and uses thereof 韩国化学研究院 2023-08-01 CN disclosed