Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.76 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.61 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282792 | 0.86 | CRBN (0.74) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL21751110 | 0.86 | CRBN (1.00) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL283113 | 0.86 | CRBN (0.74) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL4778581 | 0.85 | CRBN (0.73) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL26646479 | 0.84 | CRBN (0.77) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL4781353 | 0.84 | CRBN (0.77) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL21751086 | 0.82 | CRBN (0.69) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL29923298 | 0.81 | CRBN (1.00) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL17169744 | 0.81 | CRBN (1.00) | CRBNDDB1IKZF3BRD4 | |
| Hydrochloric Acid SCHEMBL19359358 | 0.80 | CRBN (0.97) | CRBNDDB1IKZF3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192878-B2 | Piperidine-2,6-dione derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-12-07 | — | — | US | disclosed |
| US-20200062730-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062730-A1 | NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF | CRBN, PDCD11, CD47 | CRBN 1/4885DDB1 153/4885IKZF3 969/4885 |
| US-11192878-B2 | Piperidine-2,6-dione derivative and use thereof | CRBN, PDCD11, CD47 | CRBN 1/4885DDB1 196/4885IKZF3 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.