Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.73 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.60 |
| ▸ | BRD4 | O60885 | 2/20 | 0.59 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781353 | 0.92 | CRBN (0.77) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL26646479 | 0.87 | CRBN (0.77) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL21769114 | 0.85 | CRBN (0.76) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL4778728 | 0.85 | CRBN (0.74) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL282792 | 0.84 | CRBN (0.74) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL21751110 | 0.84 | CRBN (1.00) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL283113 | 0.84 | CRBN (0.74) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL29923298 | 0.84 | CRBN (1.00) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL17169744 | 0.84 | CRBN (1.00) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19359358 | 0.83 | CRBN (0.97) | CRBNDDB1BRD4IKZF3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | disclosed |