Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.83 |
| ▸ | PIK3CD | O00329 | 17/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884100 | 0.91 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884101 | 0.85 | PIK3CG (0.90) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884102 | 0.83 | PIK3CG (0.85) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL28392472 | 0.82 | PIK3CG (0.69) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884074 | 0.81 | PIK3CG (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884069 | 0.81 | PIK3CG (0.73) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL21769549 | 0.81 | PIK3CD (0.59) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884073 | 0.81 | PIK3CG (0.82) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884089 | 0.81 | PIK3CG (0.81) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884087 | 0.81 | PIK3CG (0.81) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613743-A1 | PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES | Intellikine, LLC (US) | 2020-02-26 | — | — | EP | disclosed |