Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884103 | 0.90 | PIK3CD (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884102 | 0.86 | PIK3CG (0.85) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL18708722 | 0.86 | PIK3CG (0.77) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884101 | 0.84 | PIK3CG (0.90) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL20725920 | 0.83 | PIK3CD (0.74) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884090 | 0.83 | PIK3CD (0.81) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL21028492 | 0.82 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL13781706 | 0.82 | PIK3CG (0.76) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9924613 | 0.82 | PIK3CG (0.76) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL21769520 | 0.82 | PIK3CG (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153905-A | PI3K protein kinase inhibitors, in particular delta inhibitors and/or gamma inhibitors | 理森制药股份公司 | 2020-05-15 | — | — | CN | claimed |