Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.72 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.68 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.59 |
| ▸ | PRKDC | P78527 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884185 | 0.94 | PIK3CD (0.74) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL9884099 | 0.90 | PIK3CD (0.81) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL9884113 | 0.90 | PIK3CG (0.78) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL9884090 | 0.90 | PIK3CD (0.81) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL9884109 | 0.89 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL13781706 | 0.88 | PIK3CG (0.76) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL9924613 | 0.88 | PIK3CG (0.76) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL9883990 | 0.87 | PIK3CG (0.73) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL19418809 | 0.87 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC | |
| SCHEMBL9884218 | 0.87 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3CBPIK3CAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613743-A1 | PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES | Intellikine, LLC (US) | 2020-02-26 | — | — | EP | disclosed |