Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18766362 | 0.85 | FASN (0.42) | FASNSIGMAR1OPRM1CHRNA7 | |
| SCHEMBL738548 | 0.83 | FASN (0.41) | FASNSIGMAR1OPRM1CHRNA7 | |
| SCHEMBL18766334 | 0.82 | FASN (0.40) | FASNSIGMAR1OPRM1CHRNA7 | |
| Hydrochloric Acid SCHEMBL14720614 | 0.82 | FASN (0.40) | FASNSIGMAR1OPRM1CHRNA7 | |
| SCHEMBL21748171 | 0.79 | FASN (0.39) | FASNSIGMAR1CHRNA7 | |
| SCHEMBL18785097 | 0.79 | FASN (0.39) | FASNSIGMAR1CHRNA7 | |
| SCHEMBL23015945 | 0.77 | FASN (0.42) | FASNSIGMAR1OPRM1KCNH2 | |
| SCHEMBL20621593 | 0.77 | SIGMAR1 (0.42) | FASNSIGMAR1OPRM1KCNH2 | |
| SCHEMBL20621649 | 0.77 | SIGMAR1 (0.42) | FASNSIGMAR1OPRM1KCNH2 | |
| SCHEMBL20621596 | 0.76 | SIGMAR1 (0.63) | FASNSIGMAR1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365345-B1 | OXA-AZASPIRO COMPOUNDS HAVING ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2020-02-26 | — | — | EP | disclosed |