⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161288 | 0.94 | — | — | |
| SCHEMBL20161109 | 0.85 | PLA2G7 (0.31) | — | |
| SCHEMBL20140185 | 0.83 | — | — | |
| SCHEMBL20148884 | 0.81 | HIF1A (0.38) | — | |
| SCHEMBL21787428 | 0.79 | — | — | |
| SCHEMBL21787415 | 0.78 | TLR7 (0.30) | — | |
| SCHEMBL20148907 | 0.76 | SSTR4 (0.31) | — | |
| SCHEMBL20140188 | 0.76 | TLR7 (0.30) | — | |
| SCHEMBL20161104 | 0.72 | PRMT5 (0.30) | — | |
| SCHEMBL20141268 | 0.72 | HIF1A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017515-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-20 | — | — | US | disclosed |
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200071318-A1 | SGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-03-05 | — | — | US | disclosed |