Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27845801 | 0.96 | DNM1 (0.54) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL30884803 | 0.87 | SLC22A1 (0.50) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL8074198 | 0.84 | SLC22A1 (0.52) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL6363681 | 0.81 | HTT (0.60) | DNM1HSP90AA1RAD52 | |
| Bromide SCHEMBL11820808 | 0.79 | DNM1 (0.89) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL5087088 | 0.79 | DNM1 (0.89) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL6827078 | 0.79 | DNM1 (0.89) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL5088585 | 0.79 | DNM1 (0.89) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL5085169 | 0.79 | DNM1 (0.89) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL5091560 | 0.79 | DNM1 (0.89) | DNM1ALDH1A1TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114011390-B | Preparation method and application of porous zeolite adsorbent | 江苏埃夫信自动化工程有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114011390-A | Preparation method and application of porous zeolite adsorbent | 江苏埃夫信自动化工程有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-109264738-B | Method for synthesizing mesoporous ETS-10 zeolite containing metal without template agent | 中国石油天然气股份有限公司 | 2021-03-09 | — | — | CN | disclosed |
| US-10710886-B2 | Methods for synthesizing mesoporous zeolite ETS-10 containing metal without a templating agent | PETROCHINA COMPANY LIMITED (CN) | 2020-07-14 | — | — | US | disclosed |
| CN-107601520-B | Preparation method of ETS-10 molecular sieve | 中国科学院上海高等研究院 | 2020-03-31 | — | — | CN | disclosed |
| US-20200071174-A1 | Methods for Synthesizing Mesoporous Zeolite ETS-10 Containing Metal Without a Templating Agent | PETROCHINA COMPANY LIMITED (CN) | 2020-03-05 | — | — | US | disclosed |
| CN-104229819-A | Synthetic method of strongly-alkaline mesoporous ETS-10 zeolite molecular sieve | UNIV WENZHOU | 2014-12-24 | — | — | CN | disclosed |