Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867768 | 1.00 | KDM1A (0.41) | KDM1AMAOBEZH2SLC6A4SLC6A2 | |
| SCHEMBL19091464 | 1.00 | KDM1A (0.41) | KDM1AMAOBEZH2SLC6A4SLC6A2 | |
| SCHEMBL21784349 | 1.00 | KDM1A (0.41) | KDM1AMAOBEZH2SLC6A4SLC6A2 | |
| SCHEMBL18817746 | 1.00 | KDM1A (0.41) | KDM1AMAOBEZH2SLC6A4SLC6A2 | |
| SCHEMBL18817744 | 1.00 | KDM1A (0.41) | KDM1AMAOBEZH2SLC6A4SLC6A2 | |
| SCHEMBL19025431 | 0.86 | KDM1A (0.39) | KDM1AMAOBEZH2SLC6A4SLC6A2 | |
| SCHEMBL28272985 | 0.86 | KDM1A (0.41) | KDM1AMAOBEZH2MAOAHDAC8 | |
| SCHEMBL20134529 | 0.85 | SLC6A2 (0.42) | KDM1AMAOBSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19609147 | 0.83 | KDM1A (0.42) | KDM1AMAOBSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23856027 | 0.82 | KDM1A (0.43) | KDM1AMAOBSLC6A4SLC6A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512064-B2 | Salts of an LSD1 inhibitor and processes for preparing the same | INCYTE CORPORATION (US) | 2022-11-29 | — | — | US | disclosed |
| US-10968200-B2 | Salts of an LSD1 inhibitor and processes for preparing the same | INCYTE CORPORATION (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200071289-A1 | SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME | WILMINGTON PHARMATECH | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512064-B2 | Salts of an LSD1 inhibitor and processes for preparing the same | KDM1A, KDM1B, KDM2A | KDM1A 1/4885MAOB 386/4885EZH2 33/4885 |
| US-20200071289-A1 | SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME | KDM1A, KDM1B, KDM2A | KDM1A 1/4885MAOB 386/4885EZH2 33/4885 |
| US-10968200-B2 | Salts of an LSD1 inhibitor and processes for preparing the same | KDM1A, KDM1B, KDM2A | KDM1A 1/4885MAOB 386/4885EZH2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.