Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19026233 | 0.88 | KDM1A (0.46) | KDM1AMAOBGPR119HSD11B1CCR5 | |
| SCHEMBL18845585 | 0.88 | KDM1A (0.43) | CHRM3CHRM4CHRM5CHRM1KDM1A | |
| SCHEMBL19025438 | 0.87 | KDM1A (0.46) | CHRM3KDM1AHSD11B1CCR5 | |
| SCHEMBL19025219 | 0.87 | KDM1A (0.49) | KDM1ACCR5 | |
| SCHEMBL21784350 | 0.86 | KDM1A (0.50) | KDM1AGPR119USP30HSD11B1 | |
| SCHEMBL19025342 | 0.86 | KDM1A (0.50) | KDM1AGPR119USP30HSD11B1 | |
| SCHEMBL21784423 | 0.86 | KDM1A (0.50) | KDM1AGPR119USP30HSD11B1 | |
| SCHEMBL21784353 | 0.86 | KDM1A (0.50) | KDM1AGPR119USP30HSD11B1 | |
| SCHEMBL23867768 | 0.85 | KDM1A (0.41) | SLC6A2SLC6A4SLC6A3CHRM3KDM1A | |
| SCHEMBL21775670 | 0.85 | KDM1A (0.41) | SLC6A2SLC6A4SLC6A3CHRM3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233152-B2 | LSD1 inhibitors | Mirati Therapeutics, Inc. (US) | 2019-03-19 | — | — | US | disclosed |
| US-20180127369-A1 | LSD1 Inhibitors | Mirati Therapeutics, Inc. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233152-B2 | LSD1 inhibitors | KDM1B, KDM1A, KDM3A | SLC6A2 3576/4885SLC6A4 3738/4885SLC6A3 3739/4885 |
| US-20180127369-A1 | LSD1 Inhibitors | KDM1B, KDM1A, KDM3A | SLC6A2 3576/4885SLC6A4 3738/4885SLC6A3 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.