Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12122172 | 0.79 | CHRM2 (0.35) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL5114014 | 0.79 | TSHR (0.42) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL17294371 | 0.79 | TSHR (0.42) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL12122163 | 0.79 | TSHR (0.42) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL20776443 | 0.74 | CHRM2 (0.32) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL20776509 | 0.74 | CHRM2 (0.32) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL18911606 | 0.74 | PDK1 (0.37) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL21727736 | 0.74 | CHRM2 (0.32) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL325325 | 0.74 | CHRM2 (0.32) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL18906352 | 0.74 | PDK1 (0.37) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038279-A1 | SUBSTITUTED PYRAZOLE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 天津谷堆生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |