Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 4/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775811 | 1.00 | SSTR4 (0.47) | SSTR4SSTR1NTRK1KMT2AL3MBTL1 | |
| SCHEMBL13858620 | 0.88 | KMT2A (0.52) | NTRK1KMT2AL3MBTL1PDE4BKDM1A | |
| SCHEMBL16780873 | 0.88 | KMT2A (0.52) | NTRK1KMT2AL3MBTL1PDE4BKDM1A | |
| SCHEMBL15716485 | 0.88 | KMT2A (0.52) | NTRK1KMT2AL3MBTL1PDE4BKDM1A | |
| SCHEMBL13858621 | 0.88 | KMT2A (0.52) | NTRK1KMT2AL3MBTL1PDE4BKDM1A | |
| SCHEMBL21748604 | 0.87 | NTRK1 (0.50) | SSTR4SSTR1NTRK1AXLMERTK | |
| SCHEMBL21748605 | 0.87 | NTRK1 (0.50) | SSTR4SSTR1NTRK1AXLMERTK | |
| SCHEMBL28046375 | 0.84 | KMT2A (0.45) | NTRK1KMT2AL3MBTL1PDE4BKDM1A | |
| SCHEMBL1986245 | 0.84 | KMT2A (0.48) | SSTR4KMT2AL3MBTL1PDE4BKDM1A | |
| SCHEMBL2012023 | 0.84 | KMT2A (0.48) | SSTR4KMT2AL3MBTL1PDE4BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021834-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-01-26 | — | — | US | disclosed |
| US-11045457-B2 | Piperidinyl-3-(aryloxy)propanamides and propanoates | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20200061041-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045457-B2 | Piperidinyl-3-(aryloxy)propanamides and propanoates | SSTR4, SSTR3, NPY4R | SSTR4 1/4885SSTR1 4/4885NTRK1 1406/4885 |
| US-20200061041-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | SSTR4, SSTR3, NPY4R | SSTR4 1/4885SSTR1 4/4885NTRK1 1406/4885 |
| US-20230021834-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | SSTR4, SSTR3, NPY4R | SSTR4 1/4885SSTR1 4/4885NTRK1 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.