Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 16/20 | 0.37 |
| ▸ | MET | P08581 | 8/20 | 0.37 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21785268 | 0.79 | GSK3A (0.40) | GSK3AGSK3BAXLMETMERTK | |
| SCHEMBL23749481 | 0.77 | KDM4E (0.39) | GSK3AGSK3BAXLMETKDM4E | |
| SCHEMBL23081425 | 0.77 | GSK3A (0.38) | GSK3AGSK3BAXLMETMERTK | |
| SCHEMBL14967303 | 0.76 | NOTUM (0.47) | AXLMETMERTK | |
| SCHEMBL22511513 | 0.75 | AXL (0.47) | AXLMETMERTK | |
| SCHEMBL29536487 | 0.75 | AXL (0.47) | AXLMETMERTK | |
| Hydrochloric Acid SCHEMBL30297740 | 0.74 | AXL (0.47) | AXLMETMERTK | |
| SCHEMBL23749405 | 0.73 | GSK3A (0.37) | GSK3AGSK3BKDM4E | |
| SCHEMBL23882540 | 0.72 | AXL (0.48) | AXLMETMERTK | |
| SCHEMBL29736746 | 0.71 | GSK3A (0.42) | GSK3AGSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |
| WO-2020042618-A1 | MULTI-SUBSTITUTED PYRIDONE DERIVATIVES AND MEDICAL USE THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |