Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 11/20 | 0.37 |
| ▸ | AXL | P30530 | 9/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749405 | 0.84 | GSK3A (0.37) | KDM4EGSK3AGSK3BPOLB | |
| SCHEMBL26756058 | 0.84 | KDM4E (0.44) | KDM4EGSK3AGSK3BMETAXL | |
| SCHEMBL23749482 | 0.77 | ALDH1A1 (0.38) | KDM4EGSK3AGSK3BMETAXL | |
| SCHEMBL21776499 | 0.77 | GSK3A (0.38) | KDM4EGSK3AGSK3BMETAXL | |
| SCHEMBL21785269 | 0.77 | MET (0.43) | KDM4EGSK3AGSK3BMETAXL | |
| SCHEMBL14968894 | 0.76 | NOTUM (0.47) | KDM4EMETAXL | |
| SCHEMBL23749414 | 0.75 | MET (0.46) | METAXL | |
| SCHEMBL29626132 | 0.75 | MET (0.46) | METAXL | |
| SCHEMBL14969051 | 0.72 | NPC1 (0.48) | METAXLPOLB | |
| SCHEMBL16863292 | 0.71 | GSK3A (0.42) | KDM4EGSK3AGSK3BPOLBMAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |