Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.56 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.56 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.56 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 2/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21777693 | 1.00 | SLC6A1 (0.56) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL526440 | 0.78 | — | — | |
| SCHEMBL28224995 | 0.73 | SLC6A1 (0.58) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL24478321 | 0.72 | — | — | |
| SCHEMBL2450833 | 0.72 | — | — | |
| SCHEMBL374930 | 0.72 | — | — | |
| SCHEMBL24962406 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL21774701 | 0.71 | SLC6A1 (0.96) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL24690885 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL22655757 | 0.71 | SLC6A1 (0.96) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843727-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | Morphic Therapeutic, Inc. (US) | 2021-07-07 | — | — | EP | disclosed |
| EP-3843728-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | Morphic Therapeutic, Inc. (US) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020047207-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTICS, INC. (US) | 2020-03-05 | — | — | WO | disclosed |
| WO-2020047208-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |