Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25586130 | 0.83 | PTGS1 (0.58) | PTGS1PTGS2LMNAMGLLFAAH | |
| Acetic Acid SCHEMBL1827504 | 0.82 | PTGS1 (0.47) | PTGS1PTGS2LMNACYP2C19BLM | |
| SCHEMBL20087403 | 0.81 | PTGS1 (0.47) | PTGS1PTGS2LMNACYP2C19BLM | |
| SCHEMBL44144 | 0.81 | MGLL (0.59) | PTGS1PTGS2LMNABLMPMP22 | |
| SCHEMBL8439196 | 0.80 | PTGS1 (0.58) | PTGS1PTGS2LMNATDP1KDM4E | |
| SCHEMBL20087373 | 0.80 | PTGS1 (0.38) | PTGS1PTGS2LMNATDP1KDM4E | |
| SCHEMBL21652478 | 0.80 | CA1 (0.47) | PTGS1PTGS2LMNATDP1KDM4E | |
| SCHEMBL21652514 | 0.80 | CA1 (0.47) | PTGS1PTGS2LMNATDP1KDM4E | |
| Hydrochloric Acid SCHEMBL1535392 | 0.79 | MGLL (0.56) | PTGS1PTGS2LMNABLMPMP22 | |
| SCHEMBL20087397 | 0.79 | PTGS1 (0.45) | PTGS1PTGS2LMNACYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3844188-A1 | ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES AND THEIR USES | Ambrx, Inc. (US) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020047176-A1 | ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES AND THEIR USES | AMBRX, INC. (US) | 2020-03-05 | — | — | WO | disclosed |