Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 13/20 | 0.47 |
| ▸ | FEN1 | P39748 | 13/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18785058 | 0.85 | ALOX5AP (0.49) | ALOX5APFEN1DDR1PTGDR2 | |
| SCHEMBL18908796 | 0.81 | ALOX5AP (0.43) | ALOX5APFEN1DDR1PTGDR2 | |
| SCHEMBL18843004 | 0.80 | ALOX5AP (0.43) | ALOX5APFEN1DDR1PTGDR2 | |
| SCHEMBL21778753 | 0.78 | MRGPRX4 (0.42) | ALOX5APFEN1DDR1PTGDR2 | |
| SCHEMBL18785046 | 0.76 | ALOX5AP (0.44) | ALOX5APFEN1PTGDR2 | |
| SCHEMBL19501575 | 0.76 | ALOX5AP (0.41) | ALOX5APFEN1DDR1PTGDR2 | |
| SCHEMBL17664568 | 0.74 | PTGDR2 (0.40) | ALOX5APFEN1DDR1PTGDR2 | |
| SCHEMBL19501578 | 0.74 | DDR1 (0.48) | ALOX5APFEN1DDR1 | |
| SCHEMBL19501577 | 0.73 | ALOX5AP (0.39) | ALOX5APFEN1DDR1PTGDR2 | |
| SCHEMBL17664477 | 0.73 | SCN9A (0.41) | ALOX5APFEN1DDR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230137-A1 | PYRAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-07-29 | — | — | US | disclosed |
| US-11001567-B2 | Pyrazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-05-11 | — | — | US | disclosed |
| US-20200109128-A1 | PYRAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-04-09 | — | — | US | disclosed |
| US-10577343-B2 | Pyrazine compound and arthropod pest control agent containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230137-A1 | PYRAZINE COMPOUND | PPOX, NOX5, NISCH | ALOX5AP 381/4885FEN1 4522/4885DDR1 4833/4885 |
| US-10577343-B2 | Pyrazine compound and arthropod pest control agent containing same | PPOX, NOX5, NISCH | ALOX5AP 213/4885FEN1 4678/4885DDR1 4776/4885 |
| US-11001567-B2 | Pyrazine compound | PPOX, NOX5, NISCH | ALOX5AP 381/4885FEN1 4522/4885DDR1 4833/4885 |
| US-20200109128-A1 | PYRAZINE COMPOUND | PPOX, NOX5, NISCH | ALOX5AP 381/4885FEN1 4522/4885DDR1 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.