Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25763152 | 1.00 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL108487 | 0.86 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL17676543 | 0.86 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL14550259 | 0.86 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL25450183 | 0.77 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL17721183 | 0.74 | ATM (0.35) | PIK3CD | |
| SCHEMBL18884060 | 0.74 | ATM (0.35) | PIK3CD | |
| SCHEMBL15345248 | 0.74 | ATM (0.35) | PIK3CD | |
| SCHEMBL23641706 | 0.73 | PIK3CD (0.43) | PIK3CD | |
| SCHEMBL18470521 | 0.73 | PIK3CD (0.43) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577378-B2 | EIF4A-inhibiting compounds and methods related thereto | EFFECTOR THERAPEUTICS, INC. (US) | 2020-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577378-B2 | EIF4A-inhibiting compounds and methods related thereto | EIF4A1, EIF4A2, EIF4A3 | PIK3CD 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.