Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 7/20 | 0.70 |
| ▸ | MERTK | Q12866 | 6/20 | 0.64 |
| ▸ | AXL | P30530 | 5/20 | 0.64 |
| ▸ | MET | P08581 | 2/20 | 0.64 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.55 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.55 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18611194 | 0.84 | MAP4K3 (0.70) | MAP4K3MERTKAXLMETTYRO3 | |
| SCHEMBL2387035 | 0.82 | MAP4K3 (0.68) | MAP4K3MERTKAXLMETTYRO3 | |
| SCHEMBL28762676 | 0.82 | MERTK (0.52) | MAP4K3MERTKAXLMETTYRO3 | |
| SCHEMBL18616426 | 0.82 | BMPR1B (0.62) | MERTKAXLMETTYRO3BMPR1B | |
| SCHEMBL18579542 | 0.79 | MERTK (1.00) | MERTKAXLMETTYRO3 | |
| SCHEMBL18579605 | 0.79 | MERTK (1.00) | MERTKAXLMETTYRO3 | |
| SCHEMBL20067676 | 0.78 | MAP4K3 (0.63) | MAP4K3MERTKAXLMETTYRO3 | |
| SCHEMBL20067660 | 0.78 | MERTK (0.58) | MERTKAXLMETTYRO3BMPR1B | |
| SCHEMBL31669084 | 0.77 | MAP4K3 (0.60) | MAP4K3MERTKAXLMETTYRO3 | |
| SCHEMBL21460346 | 0.77 | MAP4K3 (0.60) | MAP4K3MERTKAXLMETTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |