Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.82 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.82 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.82 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.82 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.61 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779535 | 0.98 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL18631820 | 0.90 | HTR1A (0.83) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL22390094 | 0.90 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31197367 | 0.90 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL18290254 | 0.90 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL15929304 | 0.90 | HTR1A (1.00) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL16916968 | 0.88 | HTR1A (0.82) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL30307405 | 0.88 | HTR1A (0.82) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL15923360 | 0.86 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31197375 | 0.86 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632426-A1 | AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY | Wellstat Therapeutics Corporation (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-2950649-B1 | AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY | WELLSTAT THERAPEUTICS CORP (US) | 2020-03-04 | — | — | EP | disclosed |