Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027084 | 0.87 | HPGD (0.40) | HPGDGFERHSD17B10KDM4ETP53 | |
| SCHEMBL430140 | 0.78 | HSD17B10 (0.50) | HPGDHSD17B10KDM4EHDAC4MAPT | |
| SCHEMBL10176875 | 0.77 | ALOX15 (0.36) | KDM4EHDAC4 | |
| SCHEMBL3792647 | 0.77 | KDM4E (0.38) | KDM4EHDAC4MAPTLMNA | |
| SCHEMBL3586235 | 0.77 | MAPT (0.49) | HSD17B10KDM4EHDAC4MAPTSMN1; SMN2 | |
| SCHEMBL21004970 | 0.74 | KDM4E (0.36) | HPGDHSD17B10KDM4EHDAC4 | |
| SCHEMBL10226457 | 0.74 | PARP1 (0.48) | HPGDKDM4EHDAC4TP53SMN1; SMN2 | |
| SCHEMBL9147420 | 0.73 | MAPT (0.39) | HPGDHSD17B10KDM4EHDAC4MAPT | |
| SCHEMBL69977 | 0.73 | MAPT (0.40) | HPGDGFERHSD17B10TP53MAPT | |
| SCHEMBL9145032 | 0.72 | KDM4E (0.38) | KDM4EHDAC4SMN1; SMN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116774-A1 | COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE | 赛诺哈勃药业（成都）有限公司 | 2023-06-29 | — | — | WO | disclosed |
| EP-3483164-B1 | PYRROLOPYRROLE COMPOSITIONS AS PYRUVATE KINASE (PKR) ACTIVATORS | FORMA THERAPEUTICS INC (US) | 2020-03-04 | — | — | EP | disclosed |