Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622374 | 0.88 | SHBG (0.39) | DPP4KCNA3KDM4ECYP2D6 | |
| SCHEMBL18773810 | 0.84 | PIK3CD (0.33) | DPP4 | |
| SCHEMBL23178873 | 0.83 | KDM4E (0.40) | DPP4OPRK1OPRM1OPRD1KCNA3 | |
| SCHEMBL15133968 | 0.82 | PIK3CD (0.45) | DPP4OPRK1OPRM1OPRD1KCNA3 | |
| SCHEMBL13923638 | 0.82 | PIK3CD (0.45) | DPP4OPRK1OPRM1OPRD1KCNA3 | |
| SCHEMBL6629183 | 0.82 | PIK3CD (0.45) | DPP4OPRK1OPRM1OPRD1KCNA3 | |
| SCHEMBL26013893 | 0.80 | PDCD1 (0.40) | DPP4KCNA3 | |
| SCHEMBL25361940 | 0.78 | DPP4 (0.42) | DPP4OPRK1OPRM1OPRD1KCNA3 | |
| SCHEMBL25361108 | 0.78 | DPP4 (0.42) | DPP4OPRK1OPRM1OPRD1KCNA3 | |
| SCHEMBL25364357 | 0.78 | DPP4 (0.42) | DPP4OPRK1OPRM1OPRD1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3616753-A1 | COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |