SCHEMBL21779833

SCHEMBL21779833

NCc1ccccc1-c1nc2ccccc2s1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.63
NPC1 O15118 7/20 0.63
RAB9A P51151 7/20 0.63
ALDH1A1 P00352 6/20 0.63
SMN1; SMN2 Q16637 5/20 0.63
MAPT P10636 4/20 0.63
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
GAA P10253 4/20 0.63
TDP1 Q9NUW8 3/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
ILK Q13418 8/20 0.62
UBE2T Q9NPD8 1/20 0.54
ASIC3 Q9UHC3 1/20 0.54
APP P05067 2/20 0.50
POLB P06746 2/20 0.50
HSD17B10 Q99714 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21699657 0.83 KDM4E (0.58) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL21301181 0.83 KDM4E (0.58) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL11489855 0.83 KDM4E (0.58) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL4907798 0.83 KDM4E (0.58) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL900512 0.83 KDM4E (0.58) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL24182079 0.83 KDM4E (0.63) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL231307 0.82 KDM4E (0.75) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL21362250 0.81 KDM4E (0.59) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL8045063 0.81 KDM4E (0.55) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL12854008 0.80 KDM4E (0.72) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219497-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2023-08-02 EP disclosed
EP-3904363-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-11-03 EP disclosed
EP-3859812-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-08-04 EP disclosed
EP-3617215-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-03-04 EP disclosed
CN-108250157-A Method for synthesizing N- [2- (2-arylbenzothiazole) ] -amide under catalysis of rhodium 江西师范大学 2018-07-06 CN disclosed
CN-103992291-B Method for synthesizing 2-substituted benzothiazole derivative NANJING TECH UNIVERSITY (CN) 2016-02-10 CN disclosed
CN-102977051-B Method for synthesizing 2-substituted benzothiazole derivative UNIV HUNAN 2015-06-10 CN disclosed
CN-103992291-A Method for synthesizing 2-substituted benzothiazole derivative NANJING UNIVERSITY OF TECHNOLOGY 2014-08-20 CN disclosed
CN-102515995-B Preparation method of coupling aromatic compound UNIV ZHEJIANG TECHNOLOGY 2014-06-11 CN disclosed
CN-102977051-A Method for synthesizing 2-substituted benzothiazole derivative UNIV HUNAN 2013-03-20 CN disclosed
CN-102515995-A Preparation method of coupling aromatic compound UNIV ZHEJIANG TECHNOLOGY 2012-06-27 CN disclosed
CN-1303043-C Process for producing biaryl compound SUMITOMO CHEMICAL CO (JP) 2007-03-07 CN disclosed
CN-1642879-A Process for preparing diaryl compounds SUMITOMO CHEMICAL CO (JP) 2005-07-20 CN disclosed