Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.44 |
| ▸ | ADH1A | P07327 | 4/20 | 0.44 |
| ▸ | ADH1C | P00326 | 3/20 | 0.41 |
| ▸ | ADH7 | P40394 | 2/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266813 | 0.84 | ADH1B (0.43) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL20088181 | 0.78 | ADH1B (0.52) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL21216296 | 0.77 | — | — | |
| SCHEMBL3756245 | 0.73 | — | — | |
| SCHEMBL24313390 | 0.71 | KDM1A (0.35) | — | |
| SCHEMBL12403216 | 0.70 | — | — | |
| SCHEMBL28504210 | 0.69 | MAPT (0.47) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL22680905 | 0.69 | — | — | |
| SCHEMBL21594467 | 0.69 | — | — | |
| SCHEMBL22646198 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3616753-A1 | COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| CN-108349969-A | Substituted pyrazolo [1,5-a ] pyridine compounds as RET kinase inhibitors | 阵列生物制药公司 | 2018-07-31 | — | — | CN | disclosed |